Camptothecin hl-60
WebOct 1, 2001 · The study identifies and delineates signaling factors involved in BN80915-induced apoptosis in HL-60 cells. Cell cycle analysis of HL-60 cells treated with graded … WebThere have been some conflicting results concerning whether annexin V binds to camptothecin (CAM)-treated HL-60 cells, a commonly used model for apoptosis. We investigated the effects of culturing HL-60 cells for up to 8 h with a range of CAM concentrations. METHODS We used flow cytometry to measure cellular light scatter, …
Camptothecin hl-60
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WebCamptothecin is an alkaloid first isolated from the stem wood of the tree Camptotheca acuminata (Nyssaceae), and has potent antitumor activity. 31 Camptothecin acts by … WebCamptothecin, an quinolone alkaloid, is used as a chemotherapeutic agent in the treatment of leukemia (Jones et al., 1997). Camptothecin complexes with type I DNA …
WebHL-60 cells exposed to okadaic acid and camptothecin underwent morphological and biochemical changes typical of apoptosis, including internucleosomal DNA fragmentation and PAI-2 cleavage. Web周 珏,卢林明,张根葆(皖南医学院 1.病理解剖学教研室;2.病理生理学教研室;3.蛇毒研究所,安徽 芜湖 241002)蛇毒具有广泛的生
WebCamptothecin [47, 48]. binds non-covalently with topoisomerase-I and suppresses their catalytic activity, thus show- Vinblastine and its derivatives have been used ing anti-cancer properties. ... (HL-60, MCF-7) with IC50 value Due to the large diversity of endophytic fungi, (5.8, 20.15 μM) [92]. Incarxanthone B, a novel various novel cytotoxic ... WebThe meaning of CAMPTOTHECIN is an alkaloid C20H16N2O4 from the wood of a Chinese tree (Camptotheca acuminata of the family Nyssaceae) that has shown some …
WebJun 1, 2000 · Camptothecin (50 mM), a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I, was used as a positive control (King et al., 2000). ... Internalization of Bacillus intermedius...
WebOct 1, 2003 · (A) HL-60 cells were treated with 2 μM camptothecin only or in the presence of 20 μM calpeptin (calpain inhibitor), or 20 μM cathepsin inhibitor I (CI) or 20 μM ALLM (inhibits calpain and cathepsin) for the indicated times. (B) HL-60 cells were treated with 20 μM cisplatin, or 50 μM etoposide or 0.5 μg/mL adriamycin alone for 20 hours or ... darry boettcherWebResearch Polysaccharopeptides derived from Coriolus versicolor potentiate the S-phase specific cytotoxicity of Camptothecin (CPT) on human leukemia HL-60 cells Jennifer Man-Fan. article as: Wan et al., Polysaccharopeptides derived from. properly cited. Research Polysaccharopeptides derived from Coriolus versicolor potentiate the S-phase ... darry asoiafWebAug 15, 2024 · The IC 50 values on the HL60 cells are comparable to SN38 and 9-N - (2′-hydroxyethyl)methyl substituted compound 2b. Table 1. IC 50 values of Irinotecan (1c), SN38 (1d) and SN38 derivatives 2a-j. nontoxic - lack of cell viability decrease/toxicity in the studied compound concentration range. darry appearanceWebOct 21, 2024 · New 2,3-disubstituted thieno[2,3-d]pyrimidin-4(3H)-ones were synthesized via a one-pot reaction from 2H-thieno[2,3-d] [1,3]oxazine-2,4(1H)-diones, aromatic aldehydes, and benzylamine or 4-hydroxylbezylamine. The obtained compounds were tested in vitro for cancer cell growth inhibition. Compound 19 can inhibit all four types of tested cancer … bissell 14.4v cordless stick vacuumWebFounded. 1932. Founder. Harold L. Green. Defunct. 1990s. Fate. Closed as part of parent company ( McCrory Stores) bankruptcy in 2001. H. L. Green was a five and dime store … bissell 12 shampoo carpetWebNov 1, 2002 · The role of mitochondria in HL-60 apoptosis was explored using an inhibitor of oxidative phosphorylation, antimycin A (AMA). Methods: Changes in cell light scatter, … darry bouieWebFeb 1, 2008 · In the present study, we investigated the role of recombinant human phospholipase D2 (rhPLD2) on proliferation and apoptosis in human leukemia HL‐60 cells which induced by camptothecin. Our research demonstrated that various concentrations of rhPLD2 inhibit the growth of HL‐60 cells in a dose‐dependent manner, and rhPLD2 plus … bissell 1400m little green vacuum cleaner