WebGrapefruit can block an enzyme that helps your body break down certain medicines. If this enzyme is blocked, too much medication could remain and build up in your bloodstream, causing too-high levels. Some of the medications whose metabolism can be affected by grapefruit include: atorvastatin, lovastatin and simvastatin (cholesterol-lowering drugs) WebJun 14, 2024 · A: Certain classes of drugs — most notably statins — are metabolized (broken down) in your intestines by an enzyme called CYP3A, which normally reduces the amount of drug that enters your …
Statin Side Effects, including Lipitor (atorvastatin) on RxList.com
WebSome drugs, like certain statins used to lower cholesterol, are broken down by enzymes. As shown above, grapefruit juice can block the action of these enzymes, increasing the amount of drug in the body and may cause more side effects. Other drugs, like fexofenadine, are moved by transporters into the body’s cells. WebStatins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease.They are the most common cholesterol-lowering drugs. Low-density lipoprotein (LDL) carriers of cholesterol play a key role in the development of atherosclerosis and … mc of avon llc
Grapefruit Juice and Statins - PubMed
WebSep 30, 2024 · Atorvastatin is a cholesterol-lowering medication that blocks the production of cholesterol. ... pomegranates, pomelos, and Seville oranges can also interact with some medications, including … WebApr 17, 2024 · The most adverse side effect of consuming grapefruit while taking statins is rhabdomyolysis, a breakdown of muscle tissue that can be dangerous for kidneys and cause kidney failure or even death, but it is … WebMay 18, 2024 · Examples of common medications that interact with grapefruit juice include certain statin cholesterol drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin). Some immunosuppressants have been reported to … life cycle of a helminth