Pebp4 and heart

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August undefined, 2024

WebPEBP4 appears to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization. ... Anti-PEBP4 antibody (ab99468) at 1 µg/ml + Human Heart lysates at 35 µg Predicted band size: 26 kDa. WebMar 21, 2024 · PEBP4 (Phosphatidylethanolamine Binding Protein 4) is a Protein Coding gene. An important paralog of this gene is PEBP1. UniProtKB/Swiss-Prot Summary for …

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WebOct 17, 2015 · The PI3K/Akt/mTOR signaling axis may be a key molecular pathway via which PEBP4 promotes the proliferation and invasion of non-small cell lung cancer (NSCLC) … WebNov 12, 2011 · PEBP4 is expressed in the mammalian testis, heart, skeletal muscle, thyroid, liver, spinal cord, brain, adrenal gland, and bone marrow [ 14 ], and mainly participates in physiopathological processes such as membrane biosynthesis, neurodevelopment, spermatogenesis, and apoptosis [ 4 ]. secondary hyperhidrosis a comprehensive view

Diagnostic value of phosphatidylethanolamine binding protein 4 levels …

Webeffects of PEBP4 on LSCC can be neglected in most cases of LSCC, where PEBP4 demonstrated decreased expression levels. However, in the case of PEBP4 overexpression, it may contribute to the progression of LSCC and lead to the develop - ment of drug resistance. Introduction Lung cancer is a leading cause of cancer-associated mortality WebFeb 1, 2007 · PEBP4 (phosphatidylethanolamine binding protein 4) 2007-02-01 Identity HGNC PEBP4 LOCATION 8p21.3 LOCUSID 157310 ALIAS CORK-1, CORK1, GWTM1933, … Webpebp4. single cell type lung. adipose tissue bone marrow brain breast bronchus colon endometrium esophagus eye heart muscle. kidney liver lung lymph node ovary pancreas pbmc placenta prostate rectum. salivary gland skeletal muscle skin small intestine spleen stomach testis thymus tongue vascular. cell type proteome. pumpkin world hummelstown

PEBP balances apoptosis and autophagy in whitefly upon ... - Nature

Phosphatidylethanolamine binding protein 4 (PEBP4) is a …

WebMar 22, 2024 · Serum PEBP4 was high in CKD patients compared with healthy individuals. PEBP4 levels were positively correlated with pathological stage in CKD patients. PEBP4 had higher sensitivity for diagnosis of CKD than common indexes including blood urea nitrogen, creatinine and C-reactive protein. WebMar 28, 2016 · In mammalian cells, four members of PEBP, ranging from 21–25 kids, have been documented; PEBP1 is ubiquitously expressed at high levels in brain, adrenal gland and thyroid (2, 3), PEBP2 is mostly restricted to testis , PEBP3 has not yet been characterized, and PEBP4 is predominantly expressed in skeletal muscle, heart and thyroid . secondary hyperhidrosis causesWebJul 8, 2024 · Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted protein with multiple biological functions. At present, studies on PEBP4 exist mainly in the field of tumors and rarely in inflammation. This study aimed to explore the potential roles and mechanisms of PEBP4 on lipopolysaccharide (LPS)/D-galactosamine (D-GalN) - induced ALI. pumpkin world.com

"WebThe gene view histogram is a graphical view of mutations across PEBP4. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. " - Pebp4 and heart

Pebp4 and heart

Phosphatidylethanolamine‐binding protein 4 promotes the …

WebOct 26, 2024 · Furthermore, PEBP4 overexpression significantly promoted the transcriptional activity of sonic hedgehog (Shh) signaling in NSCLC cells. Further analysis showed that using cyclopamine to inhibit Shh signaling significantly ameliorated the effect on cell proliferation, invasion, and migration, as well as EMT triggered by PEBP4 overexpression. WebJul 8, 2024 · (E): PEBP4 protein expression was tested by western blotting in the heart, liver, lungs, spleen, and kidneys of WT and CKO mice. Data are presented as mean ± SD values …

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WebDec 1, 2024 · PEBP4 was identified by proteomics in urine and is increased in IgAN urine and serum. A: LC-MS/MS Proteomics analysis of healthy donor and IgAN patient urine identified 19 lysosomal proteins including PEBP4. Lysosomal proteins were isolated from identified urine proteins using gene ontology and are presented as a colour-coded protein-protein ... WebSep 15, 2012 · PEBP4 is a recently discovered member of the PEBP family. Human PEBP4 was isolated and obtained from a human bone marrow stromal cell cDNA library through …

WebSep 2, 2024 · Phosphatidylethanolamine-binding protein 4 (PEBP4) is a secreted protein involved in regulating many molecular pathways, whereas its roles in diseases including hepatic fibrosis remain undefined. The nuclear factor-κappa B (NF-κB) signaling pathway has been found to be involved in the development of liver fibrosis. WebJan 20, 2024 · Interaction between whitefly PEBP4 and TYLCV CP suppresses phosphorylation of MAPK cascade, activating apoptosis. TYLCV CP liberates PEBP4 …

WebSep 2, 2024 · Phosphatidylethanolamine-binding protein 4 (PEBP4) is a secreted protein involved in regulating many molecular pathways, whereas its roles in diseases including hepatic fibrosis remain undefined.... WebHeart musclei. On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and …

WebPharos : Target Details - PEBP4 Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data

WebSep 2, 2024 · Phosphatidylethanolamine-binding protein 4 (PEBP4) is a newly discovered secreted protein of the PEBP family, and is expressed in multiple human tissues such as … secondary hypercoagulable state medicationsWebPEBP4 was first identified as a regulator of the MAPK pathway (5, 20). Wang et al have shown that PEBP4 interacts with Raf-1 and MEK1 and attenuates activation of MEK1. This … secondary hyperparathyroidism abbreviationWebFeb 11, 2024 · PEBP4 directly interacted with the coat protein (CP) of TYLCV Since CP has been shown to be required for successful infection 34, it was used as the bait in yeast two … pumpkin world downloadWebDec 29, 2016 · Follow Your Heart By Diamante Lavendar Oct 11, 2016. Experience Author Self-employed Jan 2013 - Present 10 years 4 months. I write young adult fantasy and adult fiction. ... secondary hyperhidrosis treatmentWebAug 8, 2024 · PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2 PEBP4 Directs the Malignant Behavior of … pumpkin world 2008Web(E): PEBP4 protein expression was tested by western blotting in the heart, liver, lungs, spleen, and kidneys of WT and CKO mice. Data are presented as mean ± SD values (n = 3). … secondary hyperparathy icd 10WebFeb 5, 2024 · PEBP4 was associated with the development and invasion of gastric cancer cells through activation of the PI3K/Akt signaling pathway knockdown of PEBP4 inhibited hypoxia-induced epithelial-to-mesenchymal transition in prostate cancer cells. this study suggested that PEBP4 might promote the progression of pancreatic ductal adenocarcinoma secondary hyperlipidemia icd 10