WebMar 3, 2024 · Thus, we concluded that the presence of a Spliced Leader sequence (either SL1 or SL2) at the 5’ end of C. elegans mRNAs generates double-stranded hairpins of … WebSL1 leaders are spliced mostly to pre-mRNAs from genes with outrons, intron-like sequences at the 59-ends of the pre-mRNAs. In contrast, SL2 leaders are nearly …
C. elegans microRNAs - WormBook - NCBI Bookshelf
WebMar 4, 2024 · The C. elegans let-7 locus produces four transcripts. (A) Major transcripts produced from the C. elegans let-7 locus, and the locations of probes used in the northern blots shown in C, and in subsequent figures. (B) Non-qRT-PCR analysis of total RNA from a mix-population of wild-type (WT) animals, using an SL1 forward primer and LCE reverse ... WebMay 24, 2005 · The number of pseudogenes in C. elegans, for example, is estimated to be 6%–12% that of functional genes [27]. Pseudogenes that express truncated proteins have the potential to interfere with functions of the genes from which they derive. We suggest that mRNA surveillance protects cells from such disruptive proteins by degrading pseudogene … brass ganesha with bell
C. elegans sequences that control trans-splicing and …
WebTwo characteristic features of Caenorhabditis elegans make it a unique model system among eukaryotes for studying RNA processing. First, approximately 70% of the genes in C. elegans undergo trans splicing during processing of the pre-mRNA. trans splicing involves the transfer of a 22-nucleotide (nt) spliced leader (SL) sequence from the SL ... WebSep 21, 2005 · The C. elegans genome encodes hundreds of miRNAs, including the founding members of the miRNA family lin-4 and let-7. Despite the abundance of C. elegans miRNAs, few miRNA targets are known and little is known … WebFeb 4, 2024 · It is evident that SLTS has a role in resolving polycistonic mRNAs in Caenorhabditis elegans, acting as a prerequisite for subsequent translation 14. In C. elegans, approximately 70% of... brass ganesha with bell wall hanging